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主要产品:检测试剂盒,抗体及重组蛋白,涵盖了细胞凋亡、细胞信号传导和细胞因子研究的各个方面
℡ 4000-520-616
℡ 4000-520-616
BioVision/DAP12 Antibody/5570R/
产品编号:5570R-
市  场 价:¥111400.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$5570.00
品      牌: BioVision
公      司:BioVision,Inc.
公司分类:
BioVision/DAP12 Antibody/5570R/
商品介绍
Antibody Target DAP12
Alternate Name DAP-12, DAP12, DAP 12, DAP12 Polyclonal Antibody, Anti-DAP12 Polyclonal antibody, DAP12 antibody, Anti-DAP12, DAP, death associated protein, KARAP, ITIM, DAP12-KIR
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide corresponding to residues surrounding amino acids 94 of mouse DAP-12
Accession # O54885
Gene ID 22177
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 30 µg (0.5 mg/ml) affinity purified rabbit anti-DAP12 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human
Application Western blot
Application & Usage Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Description:

DAP12 (KARAP) is a natural killer (NK) cell-expressed cell surface receptor and belongs to the immunoglobulin and C-type lectin superfamily. Unlike other members of this family which possess immunoreceptor tyrosine-based inhibitory motifs (ITIM), DAP12 contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and is present as a disulphide-bonded homodimer. Crosslinking of DAP 12-KIR complexes (membrane glycoproteins of the killer-cell inhibitory receptor family without an ITIM in their cytoplasmic domain) results in cellular activation.
品牌介绍

        BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者。 BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力。包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具。如不同原理和应用的细胞增殖系列方案,细胞压力应激相关通路检测试剂盒,包括蛋白质/核酸以及酶活性水平上的全系列细胞氧化损伤和修复分析手段,糖尿病以及肥胖和代谢综合症等领域研究试剂盒;还包括前沿的干细胞生物学以及表观生物学的基因调控、信号转导等研究产品和方案。BioVision的产品目前正销往全球60多个国家。

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